What duration androgen deprivation do you recommend with salvage pelvic radiotherapy for pelvic node relapse after prostatectomy?
Answer from: Radiation Oncologist at Community Practice
6 months ADT, 2 years ADT, 2 years ADT + abiraterone/prednisone seems reasonable depending on the circumstances. For example, early pelvic node recurrence for pT3b Gleason 4+5 would be a higher risk than a very late recurrence of pT2 Gleason 3+3.
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Radiation Oncologist at University of Missouri at Columbia, Ellis Fischel Cancer Cener Agree - it is reasonable to tailor the ADT to the ...
Answer from: Radiation Oncologist at Academic Institution
Agree that there is some nuance in patient and tumor features, but ultimately this is cancer that has shown it can spread at least to lymph nodes so I generally aim for 2 years and at least discuss Abiraterone. If toxicity is high then can consider cutting short
Things that push me to shorter cours...
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Medical Oncologist at Henry Ford Health I see a practice pattern at my institution to use ...
Radiation Oncologist at Memorial Sloan Kettering Cancer Center To my knowledge, there is no direct head-to-head b...
Answer from: Radiation Oncologist at Community Practice
One option may be to assess the androgen sensitivity of the recurrence by using Decipher, provided the area is amenable to biopsy. The result would offer the potential to tailor ADT to the patient.
Answer from: Radiation Oncologist at Community Practice
I use the gleason score of the resected cancer to determine the length of hormonal therapy. If we base our duration of hormonal ablation on the gleason score for primary treatment, why wouldn't we do the same for a nodal "recurrence", which is really untreated primary disease that was present at the...
Agree - it is reasonable to tailor the ADT to the ...