How does the FDA safety warning on the cardiac effects of lamotrigine, based on in vitro data, inform your clinical practice?

This question is intended to include consideration of cardiac diagnostic screening, as well as initiation & maintenance of lamotrigine, in epilepsy patients with comorbid cardiac disease.

Answer from: at Community Practice

I am aware of it and will be careful in using it with patients who have any conduction abnormalities, though that doesn't mean I won't use it. I have been using it for many years (my program during fellowship was a research site for bringing it to the US) and never had a problem with it.

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How does the FDA safety warning on the cardiac effects of lamotrigine, based on in vitro data, inform your clinical practice?

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