How important is the timing of weekly cisplatin in concurrent chemoradiation for definitive treatment of cervical cancer?
Does cisplatin need to be administered on the start date of radiation
Answer from: Medical Oncologist at Community Practice
Weekly cisplatin in concurrent chemoradiation for cervical cancer serves as a radiosensitizer. Theoretically, it makes most sense for the chemotherapy to overlap as much as possible with the radiation. This is why typically these regimens are started on a Monday, and ideally the dose of cisplatin sh...
Answer from: Radiation Oncologist at Academic Institution
I am not aware of any data that shows a difference in outcomes based on what day of the week cisplatin is given during concurrent chemoradiation.
Assuming that radiation starts on a Monday, we do prefer our med onc colleagues to give it either Monday or Tuesday as written above, but it is not manda...
Comments
Radiation Oncologist at Varian Medical Systems/Allegheny health network There are radiobiological data showing increased c...