How long can you continue chronic low dose isotretinoin for refractory acne or other conditions?

No limit.

I agree that there is not a time limit for the use of low-dose, long-term isotretinoin for the treatment of refractory acne or other conditions, but monitoring issues need to be considered. If dosing is intermittent, then minimal monitoring is required (an annual check of standard labs is probably f...

Agree with others, there are no limits. However, I do try to get these patients down to twice or three times weekly dosing as it makes me comfortable to not check routine labs or imaging, etc.