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Hematologic Malignancies • Radiation Oncology
How should a patient with perforated H. pylori negative gastric MALT be managed?
Should systemic therapy or ISRT be utilized? Is there a risk for intrabdominal spread with perforation? If the ulcer is repaired by simple oversewing, is there a notable risk for re-perforation with or after treatment?
Answer from: Radiation Oncologist at Academic Institution
Generally, the treatment for H. Pylori neg gastric MALT of limited stage is radiotherapy, dose 24-30 gy. The question presumably concerns the influence of a history of perforation on that recommendation. Data are limited but radiation induced gastric or intestinal perforation when treating lymphoma ...
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