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Topics:
Hematologic Malignancies • Medical Oncology • Leukemia • Internal Medicine • Hematology • T-Cell Lymphoma
How should one approach an incidentally found T-cell gene arrangement?
Work-up was performed for isolated anemia which resolved to >11 g/dl after the reversible cause was treated.
Answer from: Medical Oncologist at Academic Institution
When I see an incidental T-cell clonal rearrangement without any manifestation, my first question is how was this being measured? Many PCR-based methods have a difficult time distinguishing oligoclonal versus monoclonal T-cell populations. My favored test here is looking by flow cytometry at the T-c...
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