How would you approach a patient with relapsed Ph+ ALL and MRD positive after blinatumomab?  

There is currently no defined standard-of-care treatment for pediatric relapsed Ph+ ALL. Nevertheless, many patients with relapsed Ph+ ALL can be successfully salvaged in the TKI era (especially those who had not undergone HSCT in CR1) since the 5-year EFS of pediatric Ph+ ALL on the recently publis...