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Topics:
Pediatric Hematology/Oncology • Medical Oncology • Immunotherapy • Immune-related adverse events • Infectious Disease • C difficile • Pediatric Oncology
What infections should we rule out in patients who develop diarrhea on immunotherapy?
Chemotherapy is associated with acquiring C diff colitis. Does immunotherapy share that same risk and necessitate ruling out infection prior to anti-diarrheals and immunosuppression?
Answer from: at Academic Institution
Immunotherapy is known to be associated with immune-mediated diarrhea and colitis (IMDC). However, it remains unclear whether cancer patients undergoing immunotherapy are at a heightened risk for Clostridioides difficile colitis infection (CDI). A retrospective study focusing on patients treated wit...
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