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How would you approach persistent episcleritis/uveitis due to PR3+ GPA, which needs low dose prednisone to control, despite induction with Rituximab?
Other manifestations improved (renal function has stabilized, fatigue, arthritis, and LCV have resolved). Ophthalmologist has controlled the uveitis using Durezol and prednisolone eye drops.
Answer from: at Community Practice
In patients who have refractory inflammatory eye disease despite rituximab, I have worked with ophthalmology to determine whether baseline escalation in immunosuppressive medication is indicated or if targeted organ therapy is an option. In general, there is more urgency when there is chronic active...
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