How would you approach the treatment of cytopenia related to NK cell LGL leukemia?  

You could use filgrastim and erythropoietin but I prefer to treat the underlying leukemia with low dose methotrexate or cytoxan. It may take up to 6 months to see responses to cytotoxic agents and you would need to support the patient during this time with transfusions or growth factors. Thrombocyto...