How would you approach therapy for a localized adenoid cystic carcinoma of the breast?
Do ER/PR and HER2 markers have any role?
Answer from: Medical Oncologist at Academic Institution
ACC is a rare indolent subtype of breast cancer is usually but not always triple negative for ER, PR, HER2. Despite this available data on ACC indicates an excellent prognosis with local therapy (especially if it is node negative) only. So the absolute impact of chemotherapy is likley negligible in ...