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Radiation Oncology • Thoracic Malignancies • Medical Oncology • Internal Medicine • Pulmonology
How would you manage a patient with newly diagnosed locally advanced NSCLC and concurrent, active tuberculosis on anti-TB therapy?
After initiation of anti-TB treatment and 3 negative AFB smears, would you initiate concurrent chemoRT? Would you give sequential RT then chemo to give patient more time on the anti-TB treatment before adding immunosuppressive chemotherapy?
Answer from: Medical Oncologist at Academic Institution
Excellent question @Andrew B. Thompson! Assuming the patient is otherwise a good candidate for concurrent chemoRT, my bias would be to proceed with concurrent therapy once the 3 negative AFBs are available, rather than pursue sequential RT then chemo. This recommendation is based upon the ...
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