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Topics:
Hematologic Malignancies • Radiation Oncology • Neuro-Oncology • Lymphoma • Internal Medicine • Hematology
How would you manage a primary dural low-grade lymphoma?
Would you consider observation following surgical resection with negative margins? Would you recommend WBRT and/or ISRT? What would be your preferred dose and fractionation?
Answer from: Radiation Oncologist at Academic Institution
Primary dural low grade lymphoma is a rare presentation, usually marginal zone lymphoma, mostly scattered case reports in the literature but one recent series from Memorial Sloan Kettering (de la Fuente et al., PMID 27649904). I would rx similarly for other marginal zone sites. Local rx only, usuall...
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Answer from: Radiation Oncologist at Community Practice
There are two types of presentations:
localized or multifocal.
For localized. I would treat the involved site to 24-30 Gy in 12-15 fractions.
For multifocal, I would treat the whole brain (the last one I treated was with hippocampal sparing IMRT to 23.4 Gy at 1.8 Gy per fraction covering the enti...
Comments
Radiation Oncologist at Comprehensive Cancer Center of Nevada
@Sushil Beriwal if the bulky site was resected and...
@Sushil Beriwal if the bulky site was resected and...
Radiation Oncologist at Varian Medical Systems/Allegheny health network
Yes
Yes
Radiation Oncologist at Comprehensive Cancer Center of Nevada
Thanks!
Thanks!