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Pediatric Hematology/Oncology • Internal Medicine • Thrombosis • Hematology • Benign Hematology • Hemostasis/Thrombosis
How would you manage elevated vWF and FVIII levels in a patient with a family history of coagulopathy?
vWF and FVIII activities ~200% and were checked because of the patient's family history of "coagulopathy".
Is there any utility in repeating the tests?
How would you counsel the patient on the relationship of these levels to the patient's risk of thrombosis?
Answer from: at Academic Institution
Hard to be specific without more clinical details. I would not repeat levels. Although the higher the FVIII and VWF levels, the higher the risk of thrombosis, but there is no known specific cut-off. Currently, there is no role for empiric anticoagulation. As with all patients, DVT prophylaxis in hig...
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