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How would you modify adjuvant radiation for oral cavity SCC based on the presence of sarcomatoid features?

2 Answers
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Mednet MemberInvited Expert
Radiation Oncology · University of Michigan
Answered on

Suggest to discuss the sarcomatoid features with the pathologist. There are two possibilities:

1. Spindle cell carcinoma is a variant of squamous cell carcinoma characterized by spindled or pleomorphic cells that appear to be sarcoma but are actually epithelial. Some of these can be HPV-related and h...

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Florida
Answered on

I treat as I would a poorly differentiated SCC.

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