How would you treat a newly diagnosed male with metastatic HR+ breast cancer?

Do you give first-line CDK 4/6 inhibitors with Tamoxifen or Aromatase Inhibitor (+/- GnRH analog)?

Answer from: Medical Oncologist at Academic Institution

I would recommend CDK 4/6 with AI and GnRH analog.There's no clear evidence from studies since male breast cancer is rare (<1% of breast cancers), and most CDK studies did not include male patients. One case report was published recently by Hansra et al., PMID 31929882.FDA-approved palbociclib fo...

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Medical Oncologist at MedStar Washington Hospital Center, MedStar Georgetown University Hospital
Dr. @Mita, if a male patient progresses to metasta...

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How would you treat a newly diagnosed male with metastatic HR+ breast cancer?

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