How would you treat a patient with a granular cell tumor of the breast with positive margins following excision?  

I would recommend a re-excision to widely negative margins. I would not radiate.

This is a rare diagnosis, and recurrence has rarely been reported with incomplete excision. However, positive margins alone may not be an indication to re-resect benign granular cell tumor. MDTB discussion is key here. Reports suggest that the long-term prognosis is excellent even with positive marg...