How would you treat a patient with stage IIIA non-seminoma with an anaphylactoid reaction to etoposide during first cycle?   

Etoposide is a very important drug in the curative regimens for metastatic testis cancer. BEP, EP, and VIP all incorporate etoposide. Arguably, it is possibly the second most active agent in germ cell tumors. Furthermore, it is highly synergistic with cisplatin.  "Anaphylactoid" reactions can ...