How would you treat a Stage II gastric adenocarcinoma with de-differentiation to high grade neuroendocrine tumor post resection?
The pathology shows both adenocarcinoma and neuroendocrine features.
Answer from: Medical Oncologist at Academic Institution
This is a challenging scenario... what to do with a mixed-phenotypic tumor such as this, which is actually not all that uncommon and we all face from time to time? For a pure gastric adenocarcinoma s/p resection (stage II/III), I favor a Capox/FOLFOX-type regimen, a la the Korean phase III CLASSIC t...