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How would you treat a T4 rectal cancer invading the uterus that is causing rectal and vaginal bleeding?

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Mednet Member
Mednet Member
Radiation Oncology · Montefiore Medical Center

In this T4b locally advanced rectal cancer, I would recommend neoadjuvant chemoradiation (RT dose 45 Gy to the pelvis +/- boost to 54 Gy to the gross tumor), followed by surgery (including a hysterectomy). The bleeding should stop in the first 2 weeks of neoadjuvant therapy. You do, however, have to...

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