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If a patient achieves excellent clinical/radiographic response to neoadjuvant THP, would you omit AC and proceed with surgery?

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Mednet Member
Mednet Member
Medical Oncology · University of Texas MD Anderson Cancer Center

If a patient has had only 4 cycles of THP (similar to the NeoSphere Trial preoperative component), then the standard of care is still to proceed with anthracycline-based therapy as we do not yet know if the favorable outcome associated with pCR applies to abbreviated therapy. However, for a patient ...

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If a patient achieves excellent clinical/radiographic response to neoadjuvant THP, would you omit AC and proceed with surgery? | Mednet