If a patient develops intermittent painless hematuria during standard prostate RT do you attribute this to cystitis or would you work it up further?   

While acute mucosal deepithelialization may be to blame, painless hematuria may unfortunately mark the beginning of a conundrum. It's good medicine to always develop a broad DDx and remember that radiation injuries are waste basket diagnoses. It's also wise to start with a UA/UCx, and if negative do...