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Radiation Oncology • Genitourinary Cancers
In a patient diagnosed with prostate cancer based on a biopsy many years ago placed on surveillance now with rising PSA, do you require repeat biopsy prior to definitive radiation treatment?
If a patient had biopsy proven gleason 6 disease 3-5 years ago and has had a slowly rising PSA to between 15-20 over the past year or 2, would you require repeat biopsy to appropriately risk categorize the patient prior to initiating treatment? If not would you empirically recommend concurrent ADT and for how long?
Answer from: Radiation Oncologist at Academic Institution
Assuming the patient is still a candidate for active treatment, then the short answer is yes, I would re-biopsy. If the patient can have a multiparametric MRI, I would obtain one before biopsy, then proceed to a 10-12 core biopsy and, in addition, target any areas suspicious for clinically significa...
I agree with all @Daniel E. Spratt has to say...
Can you clarify when you think PSA can be an appro...
I too am curious to @Howard M. Sandler's comment o...
@Daniel E. Spratt, If a rising PSA triggers multip...
There's also this paper: "Prostate-Specific Antige...