In a patient with a small cell of the esophagus in which trimodality therapy is planned what dose of preoperative radiation would you use and would you utilize BID fractionation?  

As is the case with many rare histology malignancies, there is no standard therapeutic approach to the management of small cell carcinoma of the esophagus. Nevertheless, there are small institutional experiences published on this topic to help guide decision making. Since the question refers to a pl...