In multiple myeloma patients on bortezomib and dexamethasone, who develop HZV reactivation while on HZV prophylaxis, do you stop bortezomib/dexamethasone permanently?  

It is important to make sure compliance with the drug is good. If it is drug resistance may play a role and alternative approaches can be used. Permanent discontinuation is not really an option as many drugs used for myeloma carries the same risk of zoster and if the patient needs the treatment, the...