In what situations do you utilize G-CSF in germ cell tumors or Hodgkin lymphoma patients receiving bleomycin?
There are conflicting reports of increased incidence of bleomycin-induced lung toxicity with G-CSF.
Answer from: Medical Oncologist at Community Practice
Having been both a lymphoma doctor and germ cell tumor doctor, I can tell you our experience. The current standard for poor risk germ cell tumors is to routinely include G-CSF with BEP X 4 and VIP X 4 in most high volume centers. A number of experts include growth factors routinely in good risk pati...
Answer from: Medical Oncologist at Community Practice
I will limit my comments for patients with germ cell tumors.Bleomycin containing combination regimens, such as BEP, are associated with intermediate (10-20%) risk of febrile neutropenia. Poor-risk germ cell tumor patients who receive higher-dose/intensity combination chemotherapy (such as 6 cycles o...
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