Is 80 Gy/40 Fx + ADT the new standard of care for definitive radiation of high risk prostate cancer?
GETUG-AFU 18 has shown a survival benefit over 70 Gy. There is much pressure to hypofractionate, but this is the first study showing a survival benefit with dose escalation with conventional fractionation.
Answer from: Radiation Oncologist at Community Practice
For those who want a more thorough answer, enjoy. If you want you can skip to the end for the summary: For well over a decade, we are taught that dose escalation improves biochemical control but not overall survival, while ADT improves both. Do the results of GETUG AFU-18 change this? Let's tak...
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Radiation Oncologist at Community Health Network You are the best
Radiation Oncologist at Lange-Fuhs Cancer Center Thank you!
Radiation Oncologist at UC San Diego Nicely put, @Dan. Lots of questions. But, also, cl...
Radiation Oncologist at Summit Medical Center Your answers are always very helpful and well done
Radiation Oncologist at Vanderbilt University School of Medicine What are your thoughts on the benefit of adding 2n...
Radiation Oncologist at Allan Blair Cancer Centre This!!
Radiation Oncologist at Rush Medical College of Rush University Hi @Dan, your answer is solid and very helpful. As...
Radiation Oncologist at Loma Linda University Has this been published beyond the abstract yet?
Answer from: Radiation Oncologist at Community Practice
@Simul, All data points to dose (i.e., BED) mattering for higher risk CaP. That said, for amenable patients, I dose-escalate via brachy-boost following EBRT in my practice as per ASCENDE. For non-brachy candidates being treated with definitive beam, I had recently switched from standard fx 80 G...
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Radiation Oncologist at Vanderbilt-Ingram Cancer Center Your BED calculations suggest that you are using a...
Radiation Oncologist at Vice Chair, Northside Hospital Cancer Institute Great point. Using the a/b of 1.5 accepted for pro...
Radiation Oncologist at Vanderbilt-Ingram Cancer Center For what it's worth, I wouldn't expect the a/b to ...
Radiation Oncologist at Genesis Healthcare Partners- San Diego Many of the medical insurers (at least in our area...
You are the best
Thank you!
Nicely put, @Dan. Lots of questions. But, also, cl...
Your answers are always very helpful and well done
What are your thoughts on the benefit of adding 2n...
This!!
Hi @Dan, your answer is solid and very helpful. As...
Has this been published beyond the abstract yet?