Is there a role for consolidative definitive radiation therapy for metastatic rectal adenocarcinoma with good response to systemic therapy (patient is not symptomatic)?  

Yes there definitely is. Patients with colorectal cancer are living much longer with aggressive treatment of metastatic disease and active chemotherapy. "Definitive" CXRT is really a neoadjuvant/palliative dose, 50.4 Gy in 28fx is the standard with 3D CRT. We would expect a 30% cCR and if that happe...