Is there a role for external radiation and/or brachytherapy in stage IVB vaginal cancer aside from palliation?

Disease involves the lungs diffusely and bilaterally.

If only palliative treatment is recommended, what should be the target volume (primary only? primary and nodes? cover inguinal LNs?)? What dose would you recommend? with or without concurrent chemo? Would vaginal brachytherapy provide any benefit after external radiation or just additional toxicity?

Answer from: Radiation Oncologist at Community Practice

I would offer palliative RT. Quad shot to the site of symptomatic disease (primary and gross node).

Answer from: Radiation Oncologist at Academic Institution

I agree. Further, what is the extent (location and type of lesions) to classify the patient as having stage IVB Ca? That could better determine the type of radiation therapy and doses.

Comments

Radiation Oncologist at University of California Irvine Medical Center
Locally, the entire anterior vagina, urethra, post...

Radiation Oncologist at Washington University School of Medicine
Because of the "central" location of some of the t...

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Is there a role for external radiation and/or brachytherapy in stage IVB vaginal cancer aside from palliation?

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