Is there a role for neoadjuvant chemotherapy in upper-tract urothelial carcinoma?

Since the benefit of neoadjuvant chemotherapy is well-defined in muscle-invasive bladder cancer, is it reasonable to consider this in upper-tract tumors as well? Are there particular subgroups of patients who may be most appropriate?

Answer from: Medical Oncologist at Academic Institution

Very common scenario with significant variability in clinical practice. There is no standard high-level evidence as compared to muscle-invasive bladder urothelial cancer, in which neoadjuvant cisplatin-based chemotherapy is the standard of care for cisplatin-eligible patients. The literature lacks d...

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Medical Oncologist at University of Tennessee Health Science Center
If a patient has a solitary kidney and has high-gr...

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Is there a role for neoadjuvant chemotherapy in upper-tract urothelial carcinoma?

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