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Hematologic Malignancies • Radiation Oncology
Is there a role for RT in localized nodal relapse of stage IV follicular lymphoma with the goal of delaying the need for additional systemic therapy?
For example, in a patient treated with multiple systemic therapies over ~10 years, would it be reasonable to use radiation to a single asymptomatic site of nodal progression?
Would your answer change if the patient had experienced significant complications with prior systemic therapy (such as systemic zoster infection)?
Does advanced age (80+) factor in to your recommendations?
Answer from: Radiation Oncologist at Academic Institution
Indolent lymphomas like follicular lymphoma typically present with diffuse disease and therapy for the disease is not curative. Oncologists vary in the aggressiveness of their treatment approach, but almost all medical oncologists would advocate for administration of systemic therapy before the pati...
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