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Is there any data to support the combination of a CDK 4/6 inhibitor with tamoxifen?
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Mednet Member
Medical Oncology · University of Wisconsin School of Medicine and Public Health
The best data for this combination comes from MONALEESA-7, which combined tamoxifen or an AI (+ ovarian suppression in all patients) with ribociclib or placebo in premenopausal women with advanced HR+, HER2 negative breast cancer. This was presented at SABCS 2017. Tamoxifen treatment was selected in...