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Is there any evidence regarding bone density gains/fracture reduction in the setting of treatment with romosozumab after a two year course of teriparatide?
Many patients are interested in romosozumab for "maximizing bone gain" and preventing future fractures. Some have had anabolic therapy with teriparatide. Is there any data supporting this approach in patients who remain high risk for fragility fractures?
Answer from: at Academic Institution
There was a study by Ebina et al., PMID 34020048 titled "To investigate the effects of prior treatment and determine the predictors of a 12-month treatment response of romosozumab (ROMO) in 148 patients with postmenopausal osteoporosis".This study was a prospective, observational, and multicenter st...
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