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Topics:
Medical Oncology • Supportive Care • Internal Medicine • Gastroenterology • Endocrinology • Obesity Medicine
Should GLP-1 agonists be held during chemotherapy?
Answer from: Medical Oncologist at Academic Institution
No. GLP-1 receptor agonists do not need to be held during chemotherapy, and there could be some benefit for these agents. For example, semaglutide is being studied in a randomized trial for mucositis prevention in BM transplant patients. [Sørum et al., PMID 39384243]In general, these agents a...
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Answer from: at Community Practice
I think there are several aspects to this question. First, is there evidence that as a class GLP-1 RAs increase the risk of cancer or worsen prognosis during cancer? I could find nothing to raise concerns about outcomes. One recent report even showed a decreased risk of some cancers with GLP-1 RA co...
Answer from: at Community Practice
When a patient experiences a significant change in their health status, it's essential to re-evaluate the risk-benefit balance of their prescribed GLP-1RA therapy. Key factors to consider include:
Continued Need: Does the patient still have a clinical indication for GLP-1RA treatment?
Tolerabili...