Should one perform a sentinel node biopsy in a clinically negative axilla prior to neoadjuvant chemotherapy?  

For an upfront clinically and radiologically negative axilla, where the SNLN is negative for disease after chemo, we don't change our RT field. For an upfront clinically and radiologically negative or positive axilla where SNLN is positive even after chemo, then normally they undergo full dissectio...

In the past there was some value in knowing nodal status before NACT, as the oncologist would decide about chemo based on nodal status. That argument has lost its relevance as now most often chemo is decided by tumor type and biological information rather than anatomical information. Avoiding s...