What additional therapies would you consider in a pregnant woman with Bechet's on an antiTNF and azathioprine who has uncontrolled non-pulmonary large vessel vasculitis?
Vasculitis activity has been assessed with serial CTA of the chest and head/neck. She has existing right axillary artery disease and new areas of involvement in the right common carotid.
Answer from: at Academic Institution
BD often improves with pregnancy, so this scenario is not typical but certainly possible. Revising the diagnosis may still be worthwhile. In any case, checking anti-TNF through levels and testing for anti-anti-TNF antibodies seem reasonable as the first steps. Increasing the anti-TNF dose and dosing...