What adjuvant therapy do you recommend for stage III colon cancer patients unable to tolerate 5FU regardless of modality/dose reduction?  

There is no high-quality evidence to support adjuvant chemotherapy for colorectal cancer with a non-fluoropyrimidine regimen. For patients at high risk for colon cancer recurrence, effort should be taken to find a dose or mode of administration that is feasible. For instance, bolus administration of...