What are your top takeaways in GU Cancers from ASCO 2023?
Answer from: Medical Oncologist at Academic Institution
THOR study. Improved overall survival (HR 0.64 p=0.005) and PFS (HR 0.58 p=0.0002) of the oral FGFR tyrosine kinase inhibitor erdafitinib in FGFR altered metastatic urothelial carcinoma over chemotherapy. Establishes a new standard of care in the second/third/fourth line setting after failure of c...
Answer from: Medical Oncologist at Academic Institution
TALAPRO-2 - Further validation of the use of a PARP inhibitor + and AR pathway inhibitor in men with CRPC and an HRR mutation (esp BRCA 1 and 2).
CONTACT-03 - No benefit to adding Atezolizumab to Cabozantinib in second line after immunotherapy in patients with metastatic ccRCC.
Development and v...