What chemotherapy regimen would you recommend for high risk ER+/Her2- LN negative breast cancer with high genomic risk disease?
I.e. according to Mammaprint test?
Answer from: Medical Oncologist at Academic Institution
For the patient described, with high genomic risk but otherwise good-risk features (ER positive, HER2 negative, node negative) I would recommend TC x 4 cycles as reported in Jones et al (JCO 2009, 27:1177). The use of anthracycline plus taxane adds benefit overall as shown in the ABC trials, but for...
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Medical Oncologist at Medical College of Wisconsin Comment - For genomic risk assessment, I generally...
Comment - For genomic risk assessment, I generally...