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Hematologic Malignancies • Radiation Oncology
What consolidative radiation volumes and dose would you use for plasmablastic lymphoma of the L maxilla s/p incisional biopsy and 6 cycles of EPOCH-R?
Would 5000 cGy ISRT be appropriate? Would you include the entire maxilla to 3000 cGy and cone down or just treat the post incisional biopsy site with a margin?
Answer from: Radiation Oncologist at Academic Institution
Plasmablastic lymphomas are particularly aggressive NHLs with features of both plasma cell neoplasms (e.g., CD138 positive) and B-cell lymphomas, but they are usually CD20 negative. They frequently arise in the oral cavity. Underlying immunodeficiency such as HIV infection is common. There is arguab...
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