What dose constraints do you recommend for the heart when treating an intrahepatic cholagiocarcionma with ablative (15 fx) techniques when the tumor is adjacent to the right atrium?   

This is a really interesting and great question. The primary considerations for heart dose are prognosis from the cancer in the best case scenario and the risks of subacute and late toxicity. Since the 5yr OS even of resected IHCC is only 25%, that is the best case assumption for ablative RT. 70% of...