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What dose of radiotherapy do you use for low volume Castleman's disease?
I have a patient with low volume disease of Castleman's disease with cervical lymphadenopathy and tonsillar hyperplasia that is suspicious but not biopsy proven (evaluated by ENT who did not recommend biopsy or surgery). Although the literature of case reports generally uses 40Gy, are there any experience with lower dose RT for low volume disease, especially given that the tonsillar hyperplasia is not proven?
Answer from: Radiation Oncologist at Academic Institution
Reports in the literature are varied in terms of radiation dose. For scenarios such as this with low volume disease, it is probably reasonable to consider the lower end of ranges reported by others to be successful, such as 30 Gy. Careful pathology review is important for these cases as ...
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