What factors do you consider to help guide treatment for patients with high grade large cell neuroendocrine cancers of the lung?
Do you incoprate Ki67% or mitotic rate into your treatment decision, and is there any use for somatostatin based imaging such as octreoscan or gallium-dotatate PET?
Answer from: Medical Oncologist at Academic Institution
High-grade large cell neuroendocrine carcinomas make up a small and aggressive subset of lung cancers that histologically and regarding treatment responsiveness share features with both small and non-small cell carcinomas. These shared features have been borne out in recent sequencing studies of thi...