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Topics:
Radiation Oncology • Genitourinary Cancers
What high dose rectal constraints do you use when using a hypofractionated prostate regimen?
U of Alabama paper states no max dose constraints used but they try to keep V60 < 10% or 10 cc (these constraints appear to be difficult to achieve). What tips do you have or constraints do you use?
Answer from: Radiation Oncologist at Academic Institution
Of course the answer is different depending on which hypofractionated regimen that you use.If you are using the CHHiP regimen (60 Gy in 20 fractions) the trial investigators have updated their recommended constraints based on the observed toxicities in the trial.In a preproof online they have provid...
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Answer from: Radiation Oncologist at Academic Institution
When we switched towards hypofractionation for intact prostate cancer (going from 39 fx to 20 fx) we adopted a pragmatic approach towards dose constraints. Our constraints for a 78 Gy prescription [e.g. rectal V70, V65, V40 Gy get <10%, 20%, and 40%] were proportionally matched to a 60 Gy prescri...