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Topics:
General Internal Medicine • Rheumatology • Systemic lupus erythematosus • Hydroxychloroquine
What is the appropriate interval to obtain a hydroxychloroquine level after making a dosage adjustment?
Answer from: at Community Practice
Hydroxychloroquine has an initial whole-blood half-life of around 5 days, while its terminal half-life is around 40 days (Costedeau-Chalumeau et al., PMID 27745934). The former is relevant to evaluating whole blood levels after a dose change.This was confirmed in the PLUS study (see figure 2 in Cost...
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