What is the appropriate time to initiate adjuvant chemo/endocrine therapy for premenopausal ER/PR+, HER2 negative early stage breast cancer with moderate Oncotype following breast conserving surgery?   

I would think there is a reasonable window for the chemotherapy to start (which should be given first), perhaps up to as late as 10-12 weeks post op (if it has to be delayed although rare to need to wait that long). Most of the time, we have made the decision to use chemotherapy and have all the nec...