What is the best imaging study to differentiate between recurrent glioblastoma and pseudoprogression?
Answer from: Radiation Oncologist at Academic Institution
Chemo-radiation-induced pseudoprogression (Psp) and/or necrosis present with MRI findings indistinguishable from tumor recurrence on conventional contrast-enhanced MRI. However, while early progressive disease (ePD) indicates treatment failure and necessitates a change in therapy, Psp indicate succe...