Do you ever consider a third course of CNS radiation to the same area for an in-field recurrence?   

I’m assuming this is for brain metastases? If so, would be helpful to know how long and interval time of the first and second RT treatments. Would discuss this at our brain mets tumor board. Any particular reason why not surgical or LITT candidate? If this patient has a good KPS, no or minimal...

Agree with Dr. @Wang. Want multi-D discussion before any consideration of 3rd course RT. For small lesions, can consider SRS. We sometimes opt for a fractionated course (for big or small lesions). For example, 30 Gy in 10 Fx with optional dose-painting to 40 Gy depending on area and prior dose overl...