What is the most updated consensus regarding the use of pill in the pocket oral anticoagulation in paroxysmal atrial fibrillation, and populations of patients who are most likely to be considered for enrollment in clinical trials?
Which DOAC(s) could be best suited for pill in the pocket anticoagulation RCTs?
Answer from: at Community Practice
I'm not sure that there is a consensus. The best available large trial data would recommend anticoagulation based on a CHADS2Vasc score of 2 or higher, while a score of 0 patients could be off anticoagulation, and if the score is 1, patients would benefit from shared decision-making. For the CHADS2V...
This question is the hypothesis being studied in REACT. Until we have data that this is a safe and effective strategy, I believe that we should maintain continuous anticoagulation in patients who we deem to be at a substantial stroke risk.