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Breast Cancer • Medical Oncology
What is the optimal dosing schedule and duration of zoledronic acid in breast cancer patients with bone metastases?
Is a monthly schedule x 1 year, followed by q3 months, now the the standard of care, as per the recently published OPTIMIZE-2 trial?
Answer from: Medical Oncologist at Academic Institution
The short answer is YES, a monthly schedule x 1 year, followed by a dose every 3 months seems to be a reasonable standard of care. However, additional research is needed to answer the question about optimal duration of therapy and dose/schedule in years beyond the first two years of therapy.
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